Sida L. is a medicinally important genus, species of which are widely used in traditional medicine systems in India. Pharmacologically, the roots are known for their anti-tumor, anti-HIV, hepatoprotective and many other properties. Phenolic antioxidants help reduce oxidative stress occurring during the treatment of these diseases. The present study aimed to evaluate and compare the polyphenol content and antioxidant properties of eight selected Sida species from Western Ghats, India. Methanolic root extracts (10% w/v) of Sida acuta, S. cordata, S. cordifolia, S. rhombifolia, S. spinosa, S. indica, S. retusa and S. mysorensis were analyzed. Sida cordifolia had the highest total phenolic content (TPC: 1.92 ±0.10 mg CAE/g and 2.13 ±0.11 mg TAE/g), total flavonoid content (TF: 2.60 ± 0.13 mg QE/g) and also had the highest antioxidant activities in the DPPH radical. trapping (51.31 ± 2.57% RSA; TEAC: 566.25 ± 28.31 μM; AEAC: 477.80 ± 23.89 μM) and ferric reducing antioxidant power assays (TEAC: 590.67 ± 29. 53 μM; AEAC: 600.67 ± 30.03 μM). In contrast to DPPH and FRAP activity, ABTS+ antioxidant activity was highest in S. indica (TEAC: 878.44 ± 43.92 μM; AEAC 968.44 ± 48.42 μM). It was significant to note that the values ​​of AEAC (μM) for all antioxidant activities analyzed were higher than those of TEAC. The high contents of phenolic compounds in root extracts of selected Sida species are directly correlated with their antioxidant activities. In conclusion, S. cordifolia roots can be considered as a potential source of polyphenols and antioxidants. Key words: Bala, Sida, total phenolic content, total flavonoids, antioxidant activity. The genus Sida L., belonging to the Malvaceae family, includes approximately 200 species. distributed throughout...... middle of paper...... Ghats regions of Belgaum district, authenticated and reference specimens deposited at the Regional Center for Medical Research (ICMR), Belgaum, Karnataka, India for future reference . [Voch. Nos. : Sida cordata Boiss. (RMRC 475), Sida spinosa L. (RMRC 477), Sida rhombifolia L. (RMRC 479), Sida acuta Burm.f. (RMRC 484), Sida cordifolia L. (RMRC 938), Sida indica L. (RMRC 939), Sida mysorensis Weight. &Arn. (RMRC 970), Sida retusa L. (RMRC 971)]The roots of S. acuta, S. cordata, S. cordifolia, S. rhombifolia, S. spinosa, S. indica, S. retusa, S. mysorensis and S The retusa have been cleaned properly, dried in the shade and roughly powdered. The powdery materials (10 g) were extracted with methanol (100 ml) by cold maceration and the extracts obtained were concentrated under reduced pressure at 40°C using a rotary evaporator (Heidolf, Germany). These residues were stored at 4 °C until further use..