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  • Essay / Mesenchymal stem cells and their use in treatment

    Mesenchymal stem cells, by definition, can be described as multipotent, self-renewing progenitor cells with multiple pathways having the potential to differentiate into cell types of of mesodermal origin such as osteocytes, adipocytes and chrondrocytes. Say no to plagiarism. Get a tailor-made essay on “Why violent video games should not be banned”? Get an original essay They are usually isolated from bone marrow and in some cases also isolated from other tissues such as placenta, adipose tissue , amniotic fluid and umbilical cord blood. .For all types of Celluar therapy, mesenchymal stem cells have been considered the gold standard because they are readily available and also due to the fact that they can be easily expanded. The unique characteristic of their multipotency has been used in tissue repair and regenerative medicine. . Their therapeutic potential is also enormous since the secretion of their soluble factors can be used to induce an immunomodulatory environment. There is enormous interest in the application of msenchymal stem cells and they have become the stem cell of choice for regenerative medicines, part of the reason being the ease with which they can be isolated from tissues and the way they function in a wide range of diseases. Mesenchymal stem cells have been used in the treatment of bone disorders, for example in osteogenesis imperfecta and hypophosphatasia. Patients in the pediatric age group undergo allogeneic hematopoietic stem cell transplantation. After that, the transplanted bone marrow cells are engrafted and generated as functional osteoblasts leading to normal bone growth progenesis. They are also used successfully in the treatment of cardiovascular diseases. Thanks to its regenerative and immunomodulatory properties, it is considered an ideal candidate for the repair and regeneration of cardiovascular tissues. Based on the properties of modulating immune responses by mesenchymal stem cells, it is also very effective in the treatment of autoimmune diseases. Due to its regenerative capacity, it is also very effective in the treatment of liver diseases such as liver cirrhosis. Mesenchymal stem cells are genetically engineered to express various anticancer genes. Mesenchymal stem cells play an important role in developing revolutionary treatment protocols for diseases that currently do not have effective real-time treatment with all modern conveniences. They have made breakthroughs in graft-versus-host disease and cardiovascular disease due to the complexity associated with these disorders. The role of mesenchymal stem cells remains to be determined through clinical trials in myocardial infarction, stroke, liver cirrhosis, amyotrophic lateral sclerosis, and graft-versus-host disease. The main avenues of access to the therapeutic mechanisms of mesenchymal stem cells are: are increasingly in demand, particularly in musculoskeletal disorders. It is only a matter of time when therapies for non-life-threatening diseases will begin to show better results compared to standard treatment protocols. Will these MSCs be able to prove their long-term cost-effectiveness and name in the treatment regimen of all standard protocols. A particular area of ​​interest that.