Lady Macbeth delivering a soliloquy, even though a doctor and his kind lady are listening. She sleepwalks and dreams that she cannot wash off a bloodstain; this symbolizes his guilty involvement in the murder of Duncan, by his hand. This quote is significant because it shows the inner torment and guilt that invades Lady Macbeth's sleep. Previously able to think rationally about the crimes she and Macbeth commit, Lady Macbeth's emotions and conscience have caught up with her by this scene. (V.1.31-35)4. In this quote, Banquo tells Macbeth that he will help fulfill the prophecy of the strange sisters as long as it does not compromise his loyalty and allegiance to Duncan. This conversation represents the beginning of the separation of two friends and is significant because it shows how Banquo is able to resist his temptation to evil while Macbeth is not. (II.1.26-29)5. In these lines, Duncan tells Malcolm about the original Thane of Cawdor. He states that it is impossible to understand a man's inner thoughts and feelings from his face. This quote is significant because the distinction between a man's face and his heart is a theme throughout the play, especially in relation to Macbeth..