Asthma is a heterogeneous chronic disease located on chromosome 5 (5q31). [1, 2] There are approximately 100 genes linked to asthma. These genes manage the immune system and inflammation [3]. A gene known as DENND1B causes the release of an increased amount of cytokine. [4] Cytokine causes asthma symptoms. Asthma is affected by several genetic and environmental factors that can lead to life-threatening complications for people with the disease. There are two types of asthma due to phenotypes: childhood asthma and adult-onset asthma. Children with childhood asthma are atopic, meaning they are affected by allergens in their environment due to genetics [5]. They are also more sensitive to allergens due to the sensitivity of airway cells to allergens [5]. Adult-onset asthma is less common than childhood-onset asthma and is more common in men than women [5]. Adult-onset asthma largely resembles that of childhood; nevertheless, it is not affected by allergens, which is called intr...