Substance use disorders affect all social, educational, cultural, and age groups. Addiction research often focuses on the abuser and the family as a whole, but not on how it affects one's spouse. In the United States, misuse is linked to approximately 590,000 deaths and is responsible for injury or illness to nearly 40 million people each year. (Cox, R., Ketner, J. and Blow, A. 2013). The consequences resulting from this disorder are not only related to drug addicts, but also have a great influence on their behavior and other layers of their lives, especially on their wives (Salehyan, Bigdeli, and Hashemian 2011). When the husband or boyfriend has an addiction, the wife takes on the responsibilities of her spouse, causing increased stress. Marriage is generally described as a protective factor against substance use. The concept of codependency was developed to explain what happens to the spouse of an addict. The concept of codependency is a controversial topic in the counseling profession, due to the existence of several different definitions of codependency. Clinicians who work primarily with addicts believe that codependency is a valid diagnosis. Codependency appeared on the treatment scene in the 1970s and was a term developed by Alcoholics Anonymous. Codependency involves a habitual pattern of thinking, feeling, and behaving toward ourselves and others that can cause us pain (Beattie, M.). A spouse uses coping skills such as pleading, threatening, arguing, avoiding, withdrawing sexually, being forgiving, taking control or responsibility, seeking outside help, and taking steps toward separation. There is growing evidence to suggest that maladaptive patterns of thinking and behavior... middle of article ...... are tested, namely that codependency exists independently of chemical dependence and that Codependent people tend to be more depressed than non-codependent people. -codependent. The aim of the study was to systematically explore the nature of codependency by conceptualizing it as a disorder existing independently of chemical dependence. Participants were 115 Saint Louis University undergraduate students enrolled in a psychology course. All participants completed the Beck Depression Inventory, the Codependency Inventory, and the Significant Others Drug Use Survey. The results show that a significant correlation between depression and having a loved one who may be chemically dependent was observed. This study shows the symptoms experienced by codependent people. The study does not have much relevance to the current study.